Sophos and Microsoft partner to bolster SMB cybersecurity

Sophos integrates with Microsoft Defender to enhance cybersecurity for small and medium businesses.

  • Thursday, 20th November 2025 Posted 1 month ago in by Aaron Sandhu

Sophos, a notable name in cutting-edge security technology, has announced a significant integration with Microsoft's renowned security suite, including Microsoft Defender for Business and Microsoft Defender for Endpoint. This strategic move sees Sophos's Managed Detection and Response (MDR) service receive Microsoft verified Small & Medium Business (SMB) solution status through the Microsoft Intelligent Security Association (MISA).

The achievement underlines the quintessential role of partner collaboration in safeguarding small to medium enterprises against a rising tide of cyber threats. By attaining this recognition, Sophos underscores its dedication to crafting solutions tailored for managed service providers (MSPs) and their clientele.

Sophos MDR for Microsoft environments is designed to detect, contain, and neutralize potential threats within Microsoft 365 environments. The service intricately combines telemetry from various Microsoft solutions, such as Microsoft 365, Defender for Office 365, and Defender for Cloud Apps, with inputs from Sophos and a plethora of other vendors. This network is further bolstered by Sophos’s proprietary threat intelligence and round-the-clock expert monitoring, ensuring quick response to any advanced threats.

In the event of an attack within a Microsoft 365 network, the adept Sophos MDR analysts have the capability to initiate a slew of response actions—ranging from blocking user logins and terminating live sessions to disabling suspect inbox rules—which expedites threat resolution and enhances security standards.

As attacks targeting smaller businesses continue to evolve in complexity, enterprises are in search of premier security measures. With the Sophos integrations into Microsoft 365 Business Premium and Microsoft Defender for Business, managed service providers are now uniquely positioned to distribute scalable, robust security solutions directly to small business clients.


This partnership signifies an important step forward, making enterprise-grade cybersecurity attainable for organizations of all sizes, as emphasised by the main leaders of both companies. It marks a fortuitous alliance that promises to strengthen the cyber defences of SMBs as they navigate an increasingly digital world.

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